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Molecular Biology

Transcript: Oxygen when burned the carbon stored in them are released into the atmosphere Oxygen comes in and Carbon comes out Molecular Biology Atmosphere Paper/Books When the carbon is contained in an object and won't leave trees are cut down and turned in to... Sugar + Oxygen Cars The carbon along with other gasses trap the heat in the earth's atmosphere. They are called greenhouse gasses. Cellular Respiration Bench Carbon Cycle I can outline the carbon cycle Respiration/Photosynthesis I can explain the relation between respiration and photosynthesis Human Health I can discuss how humans get energy from food I can explain how to keep ourselves healthy Trees fall down and over time turn in to... Carbon comes in and Oxygen comes out Humans are also part of the carbon cycle They inhale oxygen (provided by plants) and exhale carbon plants absorb carbon and release oxygen oxygen taken in by animals along with oxygen they eat food and use both to turn in to energy use for growth and other purposes one of the uses of energy are humans mining for the fossil fuels fossil fuels are considered carbon storage burning the item that is carbon storage releases the carbon back into the atmosphere 6 cups of water required, if not: Dehydration- lack of water Respiration Equation Fossil fuels are also carbon storage until they are mined and burned to power... Carbon Storage Nutrition labels are there for the people who eat the food to know what they are taking in and how much. It is used to make sure you are eating a healthy diet. Plants Absorb the carbon in the atmosphere Through photosynthesis they take in carbon and let out oxygen Money may not grow on trees, but it is from trees Carbon Dioxide Fossil Fuels Photosynthesis Recap Carbon Dioxide + Water + energy

Molecular Biology

Transcript: Molecular biologists look for specific patterns of DNA variation. Takes sequences that are the same and different into consideration. Focus on mutation and recombination. Insects' Cell Division Molecular Distance Maps mtDNA Thank you for your time and attention. Background Study of biology at the molecular level. Used to understand the reactions between various cell systems. 2000's = study of gene structure and function became prominent field. www.news-medical.net/health/What-is-Molecular-Biology.aspx What is Molecular Biology? (2011, February 1). Retrieved September 26, 2014, from http://www.news-medical.net/health/What-is-Molecular-Biology.aspx Hutchinson, F. (2014, September 24). Insect Genomes' Analysis Challenges Universality of Cell Division Proteins. Retrieved September 26, 2014, from http://www.sciencedaily.com/releases/2014/09/140924113748.htm Important Questions that are Addressed by DNA Sequence Alighnment. (n.d.). Retrieved from http://cs.calvin.edu/activities/blasted/intro03.html Lansman, R., Shade, R., Sharpira, J., & Avise, J. (1981, January 1). The Use of Restriction Endonucleases to Measure Mitochondrial DNA Sequence Relatedness in Natural Populations. Retrieved September 26, 2014, from http://faculty.sites.uci.edu/johncavise/files/2011/03/42-mtDNA-techniques.pdf How do we use DNA to determine relatedness between species? DNA Sequence Alignment "Genomes for organisms hold a significant amount of evidence for evolution given that living species share that commonality of basic heredity systems that use DNA and RNA to pass on genes from parent to offspring." Insects' cell division mtDNA DNA sequence alignment Molecular Distance Maps Molecular Biology www.exploredna.co.uk/evolution-dna.html Examples of Evidence

PowerPoint Game Templates

Transcript: Example of a Jeopardy Template By: Laken Feeser and Rachel Chapman When creating without a template... http://www.edtechnetwork.com/powerpoint.html https://www.thebalance.com/free-family-feud-powerpoint-templates-1358184 Example of a Deal or No Deal Template PowerPoint Game Templates There are free templates for games such as jeopardy, wheel of fortune, and cash cab that can be downloaded online. However, some templates may cost more money depending on the complexity of the game. Classroom Games that Make Test Review and Memorization Fun! (n.d.). Retrieved February 17, 2017, from http://people.uncw.edu/ertzbergerj/msgames.htm Fisher, S. (n.d.). Customize a PowerPoint Game for Your Class with These Free Templates. Retrieved February 17, 2017, from https://www.thebalance.com/free-powerpoint-games-for-teachers-1358169 1. Users will begin with a lot of slides all with the same basic graphic design. 2. The, decide and create a series of questions that are to be asked during the game. 3. By hyper linking certain answers to different slides, the game jumps from slide to slide while playing the game. 4. This kind of setup is normally seen as a simple quiz show game. Example of a Wheel of Fortune Template https://www.teacherspayteachers.com/Product/Wheel-of-Riches-PowerPoint-Template-Plays-Just-Like-Wheel-of-Fortune-383606 Games can be made in order to make a fun and easy way to learn. Popular game templates include: Family Feud Millionaire Jeopardy and other quiz shows. http://www.free-power-point-templates.com/deal-powerpoint-template/ Quick video on template "Millionaire" PowerPoint Games Some games are easier to make compared to others If users are unsure whether or not downloading certain templates is safe, you can actually make your own game by just simply using PowerPoint. add logo here References Example of a Family Feud Template PowerPoint Games are a great way to introduce new concepts and ideas You can create a fun, competitive atmosphere with the use of different templates You can change and rearrange information to correlate with the topic or idea being discussed. Great with students, workers, family, etc. For example: With games like Jeopardy and Family Feud, players can pick practically any answers. The person who is running the game will have to have all of the answers in order to determine if players are correct or not. However, with a game like Who Wants to be a Millionaire, the players only have a choice between answers, A, B, C, or D. Therefore, when the player decides their answer, the person running the game clicks it, and the game will tell them whether they are right or wrong.

Molecular Biology

Transcript: B Answer Question #4 Poly A TATA box Promoter region First base 2.Missense mutation Question #4 In silence mutation http://web.expasy.org/translate/ GAC 3.Nonsense mutation http://genetics.bwh.harvard.edu/pph2/index.shtml Molecular Biology 3'-UTR STOP CODON 1.Silent mutation (Aspartic Acid) Question #2 Genomic DNA TAG(UAG) tool ALIGN TGA(UGA) A #1 GGGGGCGGGTTCCAGCGCGGGG http://www.fruitfly.org/seq_tools/promoter.html CCCCAGGGGAGGCCGAGCCCGCCGCCCGGCCCCGCG CAGGCCCCGCCCGGGACTCCCCTGCGGTCCAGGCCGCGCCCCGGGCTCCGCGCCAGCCAATGAGCGCCGCCCGGCCGGGCGTGCCCCCGCGCCCCAAGCATAAACCCTGGCGCGCTCGCGGCCCGGCACTCTTCTATAAACCACAGACTCAGAGAGAACCCACCGGGGGCGGGTTCCAGCGCGGGGATGGTGCTGTCTCCTGCCGACAAGACCAACGTCAAGGCCGCCTGGGGTAAGGTCGGCGCGCACGCTGGCGAGTATGGTGCGGAGGCCCTGGAGAGGTGAGGCTCCCTCCCCTGCTCCGACCCGGGCTCCTCGCCCGCCCGGACCCACAGGCCACCCTCAACCGTCCTGGCCCCGGACCCAAACCCCACCCCTCACTCTGCTTCTCCCCGCAGGATGTTCCTGTCCTTCCCCACCACCAAGACCTACTTCCCGCACTTCGACCTGAGCCACGGCTCTGCCCAGGTTAAGGGCCACGGCAAGAAGGTGGCCGACGCGCTGACCAACGCCGTGGCGCACGTGGACGACATGCCCAACGCGCTGTCCGCCCTGAGCGACCTGCACGCGCACAAGCTTCGGGTGGACCCGGTCAACTTCAAGGTGAGCGGCGGGCCGGGAGCGATCTGGGTCGAGGGGCGAGATGGCGCCTTCCTCGCAGGGCAGAGGATCACGCGGGTTGCGGGAGGTGTAGCGCAGGCGGCGGCTGCGGGCCTGGGCCCTCGGCCCCACTGACCCTCTTCTCTGCACAGCTCCTAAGCCACTGCCTGCTGGTGACCCTGGCCGCCCACCTCCCCGCCGAGTTCACCCCTGCGGTGCACGCCTCCCTGGACAAGTTCCTGGCTTCTGTGAGCACCGTGCTGACCTCCAAATACCGTTAAGCTGGAGCCTCGGTGGCCATGCTTCTTGCCCCTTGGGCCTCCCCCCAGCCCCTCCTCCCCTTCCTGCACCCGTACCCCCGTGGTCTTTGAATAAAGTCTGAGTGGGCGGCAGCCTGTGTGTGCCTGAGTTTTTTCCCTCAGCAAACGTGCCAGGCATGGGCGTGGACAGCAGCTGGGACACACATGGCTAGAACCTCTCT GGC not End codon promoter sequence Used clustalw tool 5'-UTR ASP -> STOP codon Question #5 Question #2 Sequence B로부터 Translation되는 A.A서열 결정 ASP -> ASP GAC (Aspartic Acid) #1 GAU GAU (Aspartic Acid) end codon 3'-UTR missense mutation이 단백질의 기능적인 변화를 초래할 수 있는지 예측하여라 TAA(UAA) Exon & Intron Start codon Question #3 Used clustalw tool Correct 5'-GTC-3' tRNA but 5'-ATC-3' tRNA (Glycine) Used clustalw tool Take home exam 2 Question #3 5'-UTR GGGGGCGGGTTCCAGCGCGGGGATGGTGCTGTCTCCTGCCGACAAGACCAACGTCAAGGCCGCCTGGGGTAAGGTCGGCGCGCACGCTGGCGAGTATGGTGCGGAGGCCCTGGAGAGGATGTTCCTGTCCTTCCCCACCACCAAGACCTACTTCCCGCACTTCGACCTGAGCCACGGCTCTGCCCAGGTTAAGGGCCACGGCAAGAAGGTGGCCGACGCGCTGACCAACGCCGTGGCGCACGTGGACGACATGCCCAACGCGCTGTCCGCCCTGAGCGACCTGCACGCGCACAAGCTTCGGGTGGACCCGGTCAACTTCAAGCTCCTAAGCCACTGCCTGCTGGTGACCCTGGCCGCCCACCTCCCCGCCGAGTTCACCCCTGCGGTGCACGCCTCCCTGGACAAGTTCCTGGCTTCTGTGAGCACCGTGCTGACCTCCAAATACCGTTAAGCTGGAGCCTCGGTGGCCATGCTTCTTGCCCCTTGGGCCTCCCCCCAGAAAAAAAAAAAAAAAAAAAAAAAAAAAA B Question #5 7th : GAC (Aspartic Acid) A GAC Genomic DNA 3번문제의 내용을 활용하여 Wobble hypothesis를 설명하라 GCTGGAGCCTCGGTGGCCATGCTTCTTGCCCCTTGGGCCTCCCCCCAG Sequence B상의 coding sequence에서 7번째 codon의 base를 하나씩 변화시켜 다음의 mutation을 유도하라 Question #1 Question #1 DNA sequnce 상에 예상되는 다음 지역을 구하여라 Aspartic Acid(GAC) Other Amino Acid Dep. Biomedical science 20133839 Lee In Chae Thank you Thank you Exon Intron Exon Intron It's is Okay because same A.A

Molecular Biology

Transcript: Dan Marthaler Molecular Biology Central Dogma Central Dogma -The process of turning DNA into RNA and then finally into protein (Morange, "The Central Dogma of Biology"). - "DNA, RNA, and proteins are polymers, so each monomer in them is attached to at most two other units" ("Central Dogma of Molecular Biology", KHAN Academy). -DNA is made up of nuclicic acids. -DNA will then make copies of itself in what is known as "replication" ("Central Dogma of Molecular Biology", KHAN Academy). - DNA is the most basic level of information DNA DNA DNA Picture DNA Picture -DNA is then copied into RNA into what is known as "transcription" ("Central Dogma of Molecular Biology", KHAN Academy). - Similar to DNA, RNA is made up of nucleic acids. RNA RNA RNA Picture RNA Picture - Different from DNA and RNA, proteins are made up of amino acids. - The last step in the process is to turn the information from the RNA into a protein throught a process called "translation"("Central Dogma of Molecular Biology", KHAN Acedemy). Protein Protein Translation Translation Sex Determinations Sex Determinations - There are primary and secondary determinations of sex in humans. - "Primary sex determination is the determination of the gonads" (Gilbert, “Chromosomal Sex Determination in Mammals.”) -Primary determination is formed by chromoses and not often influenced by the enviroment. - Both male and female have an X chromose, a female will have two XX and a male will have one X and one Y, XY. Primary Determination Primary Determination Females are XX Males are XY Females are XX Males are XY - "Secondary sex determination affects the bodily phenotype outside the gonads" (Gilbert, “Chromosomal Sex Determination in Mammals.”) -The female begins develop a cervix, vagina and mammary glands. While the male develops a penis, and prostate glands. - This secondary determination of sex is determined by the hormones. Secondary Determination Secondary Determination Strategy Strategy Competitive Advantages Competitive Advantages Case Study Before After Case Study Q&A Q A &

Molecular Biology

Transcript: Computational Biology Connection between Biology and Computer Science Biological Substances 1857 "Genetics" by Mendel 1869 Identification of "Nuclein" 1882 Discovery of chromosomes 1919 "Nuclein" components are revealed - DNA!! 1943 DNA is the "genetic material" (?) 1953 DNA is a double-helix and very complex! 1957 The "Central Dogma of Biology" 1955 - DNA sequence of bovine(cow) Insulin 1958 - Protein sequence of Myoglobin 1960 - starting to predict protein structure Atlas of sequences... 1970 - Protein Data Bank 1995 - first whole genome: Hemophilis Influenza 1996 - Yeast Genome 2001 - Human Genome Comparative Genomics Algorithms Sequence Alignment Until 2009, more than 1700 biological databases are found in the web Database of biological databases! http://www.biodbs.info/DS.html DNA, RNA & Protein sequences Protein & RNA structure Gene expression Protein localization Mutations Similarity between species Specie Specific database RefSeq OMIM - genetic disorders PDB - Protein Data Bank GenBank - Genomic Data PubMed - Literature Uni-Prot - Protein Sequences GEO - Gene Expression Algorithmic C Algorithmic Learning Enzymes Translation Models How to differentiate true phenomena from artifacts Virus Kinase Ribosome Statistics Mitosis For example... A RNA What? How to adapt/estimate/learn parameters and models describing the task from examples? Biological Processes Transcription Recombination Practice the Algorithm Meiosis Proteins G Statistics Biological Learning ligase Algorithms Adaptation Topoisomerase Evolution Polymerage Why? T Membrane Mutation DNA Replication Evolution preserves sequences, thus similar genes might have similar function Sickle Cell Anemia How do we define "similar" sequences? Use examples to define similarity Biological What is the task? How? Consider all ways to "align" one sequence against another Sugar RefSeq http://www.ncbi.nlm.nih.gov Cell Entrez http://www.ncbi.nlm.nih.gov/Entrez/ How to perform the task efficiently? DNA Genome Browser http://www.genome.ucsc.edu/ 4 Aspects Mitochondrial Electron Transport Chromosomes Glycolysis Mitochondria Nuclease Pairwise Alignment Multiple Alignment Scoring Matrix Sequence Comparison History Diffusion Krebs Cytric Acid Cycle Helicase When we compare to ~1 million sequences, what is a random match and what is true? Protein folding

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